Screening of antibacterial activity of South Brazilian Baccharis species

• Published in: Pharmaceutical biology Vol. 43; no. 5; pp. 434 - 438
• Main Authors: Oliveira, S.Q. de, Trentin, V.H, Kappel, V.D, Barelli, C, Gosmann, G, Reginatto, F.H
• Format: Journal Article
• Language: English
• Published: Lisse Informa UK Ltd 01.01.2005; Taylor & Francis; Swets & Zeitlinger
• Subjects: aerial parts; antibacterial properties; Antimicrobial activity; Baccharis; bioassays; Biological and medical sciences; broth dilution assay; disk diffusion method; General pharmacology; herbal medicines; indigenous species; MBC; Medical sciences; medicinal plants; MIC; minimum bactericidal concentration (MBC); minimum inhibitory concentration; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; phytochemicals; plant extracts; Brazil; South America; America; Antimicrobial activity; Pharmacognosy; MIC; Screening test; disk diffusion method; broth dilution assay; Antimicrobial agent; Medicinal plant; MBC; Screening; Baccharis; Plant origin; Antibacterial agent; Species
• ISSN: 1388-0209; 1744-5116
• DOI: 10.1080/13880200590963754

Abstract South Brazilian Baccharis. species were studied for antibacterial activities against Gram-positive and Gram-negative bacteria using disk diffusion and broth dilution assays. The results showed that the n.-BuOH fraction (100 µg) from Baccharis usterii. Heering exhibited inhibitory activity against Staphylococcus aureus., Enterococcus faecalis., and Enterococcus faecium.. The n.-BuOH fraction of Baccharis spicata. (Lam.) Bailon (1000 µg) was effective against S. aureus., Escherichia coli., Enterococcus faecalis., and Enterococcus faecium.. The crude extract of Baccharis trimera. (Less) A. P. de Candolle (in doses of 1000 µ/disc) showed activity against S. aureus.. The minimum bactericidal concentration (MBC) obtained from n.-BuOH fraction of B. spicata. were 50 mg/ml against S. aureus., E. coli., E. faecalis., and E. faecium.. From the crude extract of B. trimera., a MBC of 25 mg/ml was obtained against S. aureus.. The n.-BuOH fraction of B. usterii. showed a MBC of 25 mg/ml against S. aureus. and 50 mg/ml against E. faecalis. and E. faecium., while the crude extract of this plant showed a MBC of 12.5 mg/ml against S. aureus..