Gastric infiltration of diffuse large B-cell lymphoma： Endoscopic diagnosis and improvement of lesions after chemotherapy

• Published in: World journal of gastroenterology : WJG Vol. 14; no. 27; pp. 4407 - 4409
• Main Author: Sergio Zepeda-Gomez Jesus Camacho Edgar Oviedo-Cardenas Carmen Lome-Maldonado
• Format: Journal Article
• Language: English
• Published: United States Department of Gastrointestinal Endoscopy, Institute Nacional de Ciencias Medicas y Nutrición "Salvador Zubirán", Tlalpan 14000, Mexico City, Mexico%Department of Pathology, Institute Nacional de Ciencias Medicas y Nutrición "Salvador Zubirán", Tlalpan 14000, Mexico City, Mexico 21.07.2008; The WJG Press and Baishideng
• Subjects: Adult; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Biopsy; B细胞淋巴瘤; Case Report; Endoscopy - methods; Female; Humans; Lymph Nodes - pathology; Lymphoma, Large B-Cell, Diffuse - diagnosis; Lymphoma, Large B-Cell, Diffuse - drug therapy; Lymphoma, Large B-Cell, Diffuse - pathology; Medical Oncology - methods; Neoplasm Invasiveness; Neoplasm Metastasis; Stomach - pathology; Stomach Neoplasms - diagnosis; Stomach Neoplasms - drug therapy; Stomach Neoplasms - secondary; 内窥镜检查; 化学疗法; 胃浸润; 胃肿瘤; Diffuse large B-cell lymphoma,Non- Hodgkin's lymphoma; Gastric infiltration
• ISSN: 1007-9327; 2219-2840
• DOI: 10.3748/wjg.14.4407

Diffuse large B-cell lymphoma （DLBCL） is the most common histologic subtype of the non-Hodgkin’s lymphoma （NHL） accounting for about 40% of all NHLs. This is a case report about the endoscopic appearance of a DLBCL with infiltration to the stomach in a 39-year-old female. She had a 6-mo history of lumbar and left upper quadrant pain with intermittent episodes of melena. A computer tomograghy （CT） scan showed mural thickening of the gastric antrum. Endoscopic examination revealed multiple gastric ulcers. Definite diagnosis could be made by endoscopic biopsies and the patient had a good response to chemotherapy. This response correlated well with a further endoscopic follow-up. A follow-up endoscopic examination could be considered to evaluate a good response to chemotherapy in DLBCL patients with secondary gastric dissemination.