Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices
AIM: To review the literature on capsule endoscopy (CE) for detecting esophageal varices using conventional esophagogastroduodenoscopy (EGD) as the standard. METHODS: A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varic...
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Published in | World journal of gastroenterology : WJG Vol. 15; no. 10; pp. 1254 - 1258 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Department of Gastroenterology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China
14.03.2009
The WJG Press and Baishideng |
Subjects | |
Online Access | Get full text |
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Summary: | AIM: To review the literature on capsule endoscopy (CE) for detecting esophageal varices using conventional esophagogastroduodenoscopy (EGD) as the standard.
METHODS: A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varices was conducted by both computer search and manual search. Data were extracted to estimate the pooled diagnostic sensitivity and specificity. RESULTS: There were seven studies appropriate for meta-analysis in our study, involving 446 patients. The pooled sensitivity and specificity of CE for detecting esophageal varices were 85.8% and 80.5%, respectively. In subgroup analysis, the pooled sensitivity and specificity were 82.7% and 54.8% in screened patients, and 87.3% and 84.7% in the screened/ patients under surveillance, respectively. CONCLUSION: CE appears to have acceptable sensitivity and specificity in detecting esophageal varices. However, data are insufficient to determine the accurate diagnostic value of CE in the screen/ surveillance of patients alone. |
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Bibliography: | Sensitivity Specificity Esophageal capsule endoscopy R195.1 14-1219/R Meta-analysis; Esophageal varices;Esophageal capsule endoscopy; Sensitivity; Specificity Esophageal varices R571.305 Meta-analysis ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 Telephone: +86-21-25070552 Correspondence to: Zhao-Shen Li, Professor, Department of Gastroenterology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China. zhaoshenli@hotmail.com Fax: +86-21-55621735 Author contributions: Liao Z, Gao R and Lu Y contributed equally to this work; Li ZS and Liao Z designed the research; Lu Y, Gao R and Hu LH performed the research; Liao Z and Gao R collected data; Lu Y and Hu LH analyzed data; Lu Y and Gao R wrote the paper. |
ISSN: | 1007-9327 2219-2840 |
DOI: | 10.3748/wjg.15.1254 |