ELECTRON MICROSCOPIC EXAMINATION OF THE MYELINATED AXONS OF CORPUS CALLOSUM IN PERFUSED YOUNG AND OLD RATS

In this study, the myelinated axons of parts of the corpus callosums of young and old rats were examined under the electron microscope and a grading system was performed for quantiating the ultrastructural pathological changes of these axons. Except the old splenium group, the only ultrastructural p...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of neuroscience Vol. 117; no. 7; pp. 999 - 1010
Main Authors SARGON, MUSTAFA F., DENK, C. CEM, CELIK, H. HAMDI, SURUCU, H. SELCUK, ALDUR, M. MUSTAFA
Format Journal Article
LanguageEnglish
Published England Informa UK Ltd 01.07.2007
Taylor & Francis
Subjects
Aging - pathology
Animals
Axons - classification
Axons - pathology
Axons - ultrastructure
corpus callosum
Corpus Callosum - pathology
Corpus Callosum - ultrastructure
electron microscopy
grading
Male
Microscopy, Electron
myelinated axons
Nerve Fibers, Myelinated - pathology
Nerve Fibers, Myelinated - ultrastructure
rat
Rats
Rats, Sprague-Dawley
ultrastructure
Online AccessGet full text

Cover

More Information
Summary:In this study, the myelinated axons of parts of the corpus callosums of young and old rats were examined under the electron microscope and a grading system was performed for quantiating the ultrastructural pathological changes of these axons. Except the old splenium group, the only ultrastructural pathological change, observed in the myelinated axons was the separation in myelin configuration. In addition to this finding, in the old splenium group, in some of the myelinated axons, an interruption was observed in the myelin configuration. Additionally, these ultrastructural pathological findings were present in the larger sized myelinated axons of the corpus callosum.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0020-7454
1563-5279
1543-5245
DOI:10.1080/00207450600934382