Clinical implications of human papilloma virus and other biologic markers in nasopharyngeal cancer

Highlights • The study identified relatively low expression of HPV DNA overall. • P16 expression was identified in more than half of nasopharyngeal cancer patients. • P16 expression correlated with improved nasopharyngeal cancer-specific survival. • P16 may be a prognostic marker for nasopharyngeal...

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Published inOral oncology Vol. 55; pp. e7 - e10
Main Authors Kang, Hyunmo, Kwon, Minsu, Park, Jung Je, Kim, Jin Pyeong, Woo, Seung Hoon, Ahn, Seong-Ki, Lee, Jong Sil, Seo, Ji Hyun, Hwa, Jeong Seok
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.2016
Subjects
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor - metabolism
Female
Genes, p16
Genes, p53
Hematology, Oncology and Palliative Medicine
Herpesvirus 4, Human - isolation & purification
Humans
Male
Middle Aged
Nasopharyngeal Neoplasms - virology
Otolaryngology
Papillomaviridae - isolation & purification
Papillomavirus Infections - virology
Receptor, Epidermal Growth Factor
Survival Rate
Young Adult
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Summary:Highlights • The study identified relatively low expression of HPV DNA overall. • P16 expression was identified in more than half of nasopharyngeal cancer patients. • P16 expression correlated with improved nasopharyngeal cancer-specific survival. • P16 may be a prognostic marker for nasopharyngeal cancer.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2016.02.002