Staging Papillary Carcinoma of the Thyroid: Magnetic Resonance Imaging vs Ultrasound of the Neck

• Published in: Clinical radiology Vol. 55; no. 3; pp. 222 - 226
• Main Authors: KING, A.D., AHUJA, A.T., TO, E.W.H., TSE, G.M.K., METREWELI, C.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.03.2000; Elsevier
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Carcinoma, Papillary - diagnostic imaging; Carcinoma, Papillary - secondary; Disease Progression; Endocrine glands; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Lymphatic Metastasis; Magnetic Resonance Imaging - methods; Male; Medical sciences; Middle Aged; MR imaging, ultrasound, thyroid, cancer; Neck - diagnostic imaging; Neoplasm Staging - methods; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Thyroid Neoplasms - diagnostic imaging; Thyroid Neoplasms - pathology; Ultrasonography; MR imaging, ultrasound, thyroid, cancer; Endocrinopathy; Sonography; Human; Papillary carcinoma; Thyroid diseases; Stage classification; Exploration; Thyroid gland; Malignant tumor; Nuclear magnetic resonance imaging; Echography; Medical imagery; Neck
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1053/crad.1999.0373

AIM: To evaluate the role of magnetic resonance imaging (MRI) for staging local disease and lymph node metastases in papillary carcinoma of the thyroid by comparing MRI with ultrasound (US) of the neck. MATERIALS AND METHODS: Fourteen patients with papillary carcinoma underwent MRI and US. The images were prospectively reviewed for (1) identification of the primary lesion; (2) presence of multifocal thyroid disease; (3) extracapsular extension; (4) invasion into the trachea, oesophagus and major vessels; and (5) presence of lymph node metastases. Correlation was made with the surgical findings. RESULTS: The site of the primary lesion was correctly identified by US in 14 of 14 (100%) and by MRI in 13 of 14 (93%) of patients. Multifocal thyroid tumour was correctly identified by US in two of two patients (100%) and by MRI in zero of two (0%). Extracapsular extension (n=9), oesophageal invasion (n=1) and tracheal invasion (n=2) were identified by MRI in seven, zero, and one, and by US in six, zero and zero patients, respectively. Invasion of the major vessels was not seen. Metastatic cervical nodes were present in 19 nodal groups in 10 patients involving the internal jugular chain (n=10), posterior triangle (n=4) supraclavicular fossa (n=1) and central group (n=4). Both MRI and US failed to identify metastatic nodes in the central group but correctly identified 14 of the 15 nodal groups outside the central group. CONCLUSION: Ultrasound should be used as the first line of investigation for detecting the primary lesion, multifocal disease and cervical lymphadenopathy. In cases where the primary tumour is not surrounded by normal thyroid tissue MR imaging should be added to assess extracapsular spread, especially into the trachea.King, A. D. (2000). Clinical Radiology55, 222–226.