Intra-Spinal Bone Marrow Mononuclear Cells Transplantation Inhibits the Expression of Nuclear Factor-κB in Acute Transection Spinal Cord Injury in Rats

• Published in: Journal of Korean Neurosurgical Society Vol. 56; no. 5; pp. 375 - 382
• Main Authors: Shrestha, Rajiv Prasad, Qiao, Jian Min, Shen, Fu Guo, Bista, Krishna Bahadur, Zhao, Zhong Nan, Yang, Jianhua
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Neurosurgical Society 01.11.2014; 대한신경외과학회
• Subjects: Laboratory Investigation; 신경외과학; NF-κB; Inflammation; Neuroprotective agent; Spinal cord injury; Mononuclear cells; Cell transplantation

To assess the effect of bone marrow mononuclear cells (BMMNCs) transplantation in the expression of nuclear factor-κB (NF-κB) in spinal cord injury (SCI) in rats. BMMNCs were isolated from tibia and femur by a density gradient centrifugation. After establishment of acute transection SCI, rats were d...