Nuclear Medicine in Early-Stage Melanoma: Sentinel Node Biopsy—FDG-PET/CT

Sentinel node status is the most powerful prognostic factor in patients with early-stage melanoma. This review discusses several issues of clinical interest and technical points for an optimized sentinel node biopsy (SNB) procedure. The role of fluorodeoxyglucose positron emission tomography/compute...

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Published inPET clinics Vol. 6; no. 1; pp. 9 - 25
Main Authors Hindié, Elif, Sarandi, Farid, Banayan, Soraya, Groheux, David, Rubello, Domenico, Vercellino, Laetitia, Toubert, Marie-Elisabeth, Moretti, Jean-Luc, Lebbé, Céleste
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 2011
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Summary:Sentinel node status is the most powerful prognostic factor in patients with early-stage melanoma. This review discusses several issues of clinical interest and technical points for an optimized sentinel node biopsy (SNB) procedure. The role of fluorodeoxyglucose positron emission tomography/computed tomography is clearly established in patients with suspicion of locoregional or distant recurrence of melanoma before any surgical decision. However, its role at initial staging or follow-up of patients with localized disease or with positive SNB is less clear. Further research and efforts should focus on identifying which groups of patients are at specific high risk of early distant recurrence.
Bibliography:http://dx.doi.org/10.1016/j.cpet.2011.01.001
ISSN:1556-8598
1879-9809
DOI:10.1016/j.cpet.2011.01.001