Bioactivities of Novel Metal Complexes Involving B Vitamins and Glycine

In this work twelve novel mixed ligand complexes were synthesized. The complexes were formed between a metal ion (Cu(II), Cd(II), Mn(II), Fe(III), Ni(II), Pb(II)) and vitamins (B 3 and B 9) as primary ligands, and glycine as secondary ligand. Melting points, conductivities, and magnetic susceptibili...

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Published inOpen Chemistry Vol. 14; no. 1; pp. 287 - 298
Main Authors Fazary, Ahmed E., Ju, Yi-Hsu, Rajhi, Aisha Q., Alshihri, Ayed S., Alfaifi, Mohammad Y., Alshehri, Mohammed A., Saleh, Kamel A, Elbehairi, Serag Eldin I., Fawy, Khaled F., Abd-Rabboh, Hisham S. M.
Format Journal Article
LanguageEnglish
Published De Gruyter Open 01.01.2016
De Gruyter
Subjects
Bioactivities
Characterization
Folic Acid
Metal Complexes
Nicotinic Acid
Synthesis
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Summary:In this work twelve novel mixed ligand complexes were synthesized. The complexes were formed between a metal ion (Cu(II), Cd(II), Mn(II), Fe(III), Ni(II), Pb(II)) and vitamins (B 3 and B 9) as primary ligands, and glycine as secondary ligand. Melting points, conductivities, and magnetic susceptibilities of the synthesized complexes were determined and the complexes were subjected to elemental analyses. The presence of coordination water molecules in the complex was also supported by TG/DTG thermal analysis. Full elucidation of the molecular structures for the synthesized mixed ligand complexes were confirmed using detailed spectroscopic IR, H-, C-NMR, and XRD techniques. In addition, cytotoxic and antioxidant activities of the twelve synthesized solid complexes were tested to evaluate their bioactivities.
ISSN:2391-5420
2391-5420
DOI:10.1515/chem-2016-0028