The epidemiology of head and neck squamous cell carcinoma in The Netherlands during the era of HPV-related oropharyngeal squamous cell carcinoma. Is there really evidence for a change?

• Published in: Oral oncology Vol. 51; no. 10; pp. 901 - 907
• Main Authors: van Monsjou, H.S, Schaapveld, M, van den Brekel, M.W.M, Balm, A.J.M
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2015
• Subjects: Aged; Alcohol; Alphapapillomavirus - isolation & purification; Carcinoma, Squamous Cell - epidemiology; Carcinoma, Squamous Cell - virology; Epidemiology; Female; Head and neck cancer; Head and Neck Neoplasms - epidemiology; Head and Neck Neoplasms - virology; Hematology, Oncology and Palliative Medicine; HPV; Humans; Incidence; Male; Middle Aged; Netherlands - epidemiology; Oral cavity; Oropharyngeal Neoplasms - epidemiology; Oropharyngeal Neoplasms - virology; Oropharynx; Otolaryngology; The Netherlands; Tobacco; Netherlands; The Netherlands; Oral cavity; Tobacco; Head and neck cancer; Alcohol; Oropharynx; Epidemiology; HPV; Incidence
• ISSN: 1368-8375; 1879-0593
• DOI: 10.1016/j.oraloncology.2015.06.011

Highlights • We evaluate trends in incidence of oral and oropharyngeal cancer. • The incidence of oropharyngeal cancer increases. • Among females, similar increases for oral tongue and cavity were found. • Smoking and alcohol consumption are the main cause for developing oral and oropharyngeal cancer. • Improved prognosis for oropharyngeal cancer is a result of a shift to concomitant chemoradiation therapy.