Evaluation of Xpert® Norovirus Assay performance in comparison with real-time RT-PCR in hospitalized adult patients with acute gastroenteritis

Abstract Xpert® Norovirus Assay (Cepheid, Sunnyvale, CA USA) was compared with a laboratory-developed real-time RT-PCR assay for the detection of Norovirus GI and GII in hospitalized patients with acute gastroenteritis. The two assays showed a high level of concordance but Xpert® Norovirus Assay all...

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Published inDiagnostic microbiology and infectious disease Vol. 85; no. 4; pp. 426 - 427
Main Authors Rovida, Francesca, Premoli, Marta, Campanini, Giulia, Sarasini, Antonella, Baldanti, Fausto
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.08.2016
Subjects
Acute gastroenteritis
Adult
Aged
Aged, 80 and over
Caliciviridae Infections - diagnosis
Caliciviridae Infections - virology
Female
Gastroenteritis - diagnosis
Gastroenteritis - virology
Hospitalization
Humans
Infectious Disease
Internal Medicine
Male
Middle Aged
Molecular Diagnostic Techniques - methods
Norovirus
Norovirus - isolation & purification
Real-Time Polymerase Chain Reaction - methods
Reverse Transcriptase Polymerase Chain Reaction - methods
Time Factors
Xpert® Norovirus Assay
acute gastroenteritis
Xpert® Norovirus Assay
Norovirus
Acute gastroenteritis
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Summary:Abstract Xpert® Norovirus Assay (Cepheid, Sunnyvale, CA USA) was compared with a laboratory-developed real-time RT-PCR assay for the detection of Norovirus GI and GII in hospitalized patients with acute gastroenteritis. The two assays showed a high level of concordance but Xpert® Norovirus Assay allowed faster detection of Norovirus and a simpler sample handling.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2016.05.002