Non-Hodgkin's lymphoma of the lacrimal sac and concomitant pansinusitis

• Published in: Journal of laryngology and otology Vol. 112; no. 10; p. 969
• Main Authors: el-Hakim, H, Nunez, D A
• Format: Journal Article
• Language: English
• Published: England 01.10.1998
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Combined Modality Therapy; Cyclophosphamide - therapeutic use; Doxorubicin - therapeutic use; Female; Headache - etiology; HIV Seronegativity; Humans; Lacrimal Apparatus Diseases - complications; Lacrimal Apparatus Diseases - drug therapy; Lacrimal Apparatus Diseases - surgery; Lymphoma, B-Cell - complications; Lymphoma, B-Cell - drug therapy; Lymphoma, B-Cell - surgery; Lymphoma, Non-Hodgkin - complications; Lymphoma, Non-Hodgkin - drug therapy; Lymphoma, Non-Hodgkin - surgery; Middle Aged; Prednisone - therapeutic use; Sinusitis - complications; Sinusitis - drug therapy; Vincristine - therapeutic use
• ISSN: 0022-2151
• DOI: 10.1017/S0022215100142215

Paranasal sinus disease has an established propensity to breach anatomical barriers and present with orbital clinical features. Lacrimal sac lymphomas on the other hand are rare, usually present in males in the sixth decade and 50 per cent of cases have systemic lymphoma/leukaemia. Atypical presentations of lymphomas at this and other sites are reported in patients with acquired immunodeficiency syndrome (AIDS). The clinical features, investigations and treatment of a young human immunodeficiency virus (HIV) sero-negative woman with a non-Hodgkin's lymphoma localized to the lacrimal sac and presenting with a concomitant ipsilateral pansinusitis is described. The importance of submitting surgical material for pathological investigation is stressed.