Neuro-ophthalmologic Manifestations of Neuroendocrine Carcinoma

• Published in: Journal of neuro-ophthalmology Vol. 20; no. 2; pp. 106 - 110
• Main Authors: Lee, Andrew G, Chokshi, Amit, Goodman, Clay J
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins, Inc 01.06.2000; Lippincott Williams & Wilkins
• Subjects: Adult; Aged; Biological and medical sciences; Blepharoptosis - diagnosis; Carcinoma, Neuroendocrine - diagnosis; Cavernous Sinus - pathology; Diagnosis, Differential; Eye Movements; Female; Headache - diagnosis; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Neoplasm Invasiveness; Neurology; Ophthalmoplegia - diagnosis; Paranasal Sinus Neoplasms - diagnosis; Tumors of the nervous system. Phacomatoses; Vision Disorders - diagnosis; Visual Acuity; Endocrinopathy; Human; Nervous system diseases; Ptosis; Suprasellar; Cerebral disorder; Sella turcica; Case study; Eye; Symptomatology; Eye disease; Eyelid disease; Ophthalmoplegia; Complication; Oculomotor syndrome; Neuroendocrine tumor
• ISSN: 1070-8022; 1536-5166
• DOI: 10.1097/00041327-200020020-00009

The neuro-ophthalmologic findings of parasellar neuroendocrine carcinoma are reported. Two patients with parasellar neuroendocrine carcinoma had headache, ptosis, and ophthalmoplegia. In both patients, neuroimaging revealed a parasellar mass with extension into the cavernous sinus. The tumors initially were believed to be pituitary adenomas, but histopathology confirmed neuroendocrine carcinoma. Clinicians should be aware of neuroendocrine carcinoma in the differential diagnosis of sellar/parasellar lesions causing ophthalmoplegia.