Oral versus intravenous premedication for small bowel biopsy in children: effect on procedure and fluoroscopy times

Oral alimemazine and cisapride, or diazepam and cisapride, or iv midazolam and metoclopramide were given as premedication for small bowel biopsy to three groups of children from a total population of 185 individuals. The biopsy procedures were performed under intermittent fluoroscopy and times for b...

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Bibliographic Details
Published inActa pædiatrica (Oslo) Vol. 82; no. 1; p. 49
Main Authors Stenhammar, L, Wärngård, O, Lewander, P, Nordvall, M
Format Journal Article
LanguageEnglish
Published Norway 01.01.1993
Subjects
Administration, Oral
Adolescent
Biopsy
Celiac Disease - pathology
Child
Child, Preschool
Cisapride
Diazepam - administration & dosage
Fluoroscopy
Humans
Infant
Infusions, Intravenous
Intestine, Small - pathology
Metoclopramide - administration & dosage
Midazolam - administration & dosage
Piperidines - administration & dosage
Premedication - methods
Serotonin Antagonists - administration & dosage
Trimeprazine - administration & dosage
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Summary:Oral alimemazine and cisapride, or diazepam and cisapride, or iv midazolam and metoclopramide were given as premedication for small bowel biopsy to three groups of children from a total population of 185 individuals. The biopsy procedures were performed under intermittent fluoroscopy and times for both were recorded. The median biopsy procedure time was significantly shorter in children given iv midazolam and metoclopramide (6 min) compared to those given oral premedication (10 min) (p < 0.001). The median fluoroscopy time was very short in all groups, ranging between 3 and 6 s. It is concluded that iv premedication is superior to oral premedication for small bowel biopsy in children because more effective sedation is obtained.
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1993.tb12514.x