Effect of nutrition impact symptoms on oral nutritional supplements energy intake and use days in patients with head and neck cancer: A cross‐sectional study

• Published in: Cancer medicine (Malden, MA) Vol. 13; no. 10; pp. e7288 - n/a
• Main Authors: Dai, Tingting, Xian, Jinli, Li, Xuemei, Wang, Zhiqiang, Hu, Wen
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.05.2024; John Wiley and Sons Inc; Wiley
• Subjects: Adult; Aged; Body mass index; Chemotherapy; China - epidemiology; Contraindications; Cross-Sectional Studies; Deglutition Disorders - etiology; Dietary Supplements; Dysphagia; Energy; Energy Intake; Exercise; Female; Food; Head & neck cancer; Head and neck; head and neck cancer; Head and Neck Neoplasms - complications; Hospitals; Humans; Male; Malnutrition; Malnutrition - epidemiology; Malnutrition - etiology; Middle Aged; Mortality; Nutrition; nutrition impact symptoms; Nutritional Status; Nutritionists; ONS energy intake; ONS use days; Oral nutritional supplements; Pain; Patients; Radiation therapy; Variables; Vomiting; Vomiting - epidemiology; Vomiting - etiology; Xerostomia; Xerostomia - etiology; China; nutrition impact symptoms; Oral nutritional supplements; ONS use days; head and neck cancer; ONS energy intake
• ISSN: 2045-7634; 2045-7634
• DOI: 10.1002/cam4.7288

Background This study aims to explore the effect of nutritional impact symptoms (NIS) on oral nutritional supplements (ONS) energy intake and use days among head and neck cancer (HNC) patients. Methods A cross‐sectional study was conducted among HNC patients in a hospital in western China between January 2019 and June 2020. The NIS was from the Patient‐Generated Subjective Global Assessment (PG‐SGA) scale. Mann–Whitney test was used to examine the differences between different kinds of NIS and ONS use days. Binary logistic regression was used to determine the effect of NIS on ONS energy intake. Results The most prevalent four NIS were no appetite (35.3%), dysphagia (29.4%), vomiting (13.2%) and oral pain (12.5%), respectively. All patients in the study were malnutrition. Patients with xerostomia or oral pain had less ONS use days than those without these symptoms. Patients with vomiting (OR 0.09, 95% CI 0.02–0.50) or pain (OR 0.15, 95% CI 0.02–0.89) were less likely to have ONS energy intake ≥400 kcal/day than those without these symptoms after adjusting the confounding factors. In addition, one‐point increase in total NIS score was associated with a lower proportion of ONS energy intake ≥400 kcal/day (OR 0.77, 95% CI 0.59–0.99). Conclusion Xerostomia, oral pain, vomiting and pain should be strengthened and intervened to improve ONS use and nutritional status among HNC patients with malnutrition.