Comparison of IL10 and IL2 genotypes of Turkish population with other populations

Summary The human genome has been shaped by evolutionary and historical forces. Therefore, genetic polymorphisms are useful tools not only to understand the susceptibility to disease in modern populations, but the history of ancestral populations as well. For this purpose, data on genetic polymorphi...

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Bibliographic Details
Published inInternational journal of immunogenetics Vol. 36; no. 2; pp. 97 - 101
Main Authors Yazıcı, A. C., Atac, F. B., Verdi, H., Ozbek, N.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.04.2009
Subjects
Adolescent
Adult
Alleles
Gene Frequency
Genetic Markers
Genotype
Humans
Interleukin-10 - genetics
Interleukin-2 - genetics
Middle Aged
Polymorphism, Genetic
Population - genetics
Turkey
Young Adult
Turkey
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Summary:Summary The human genome has been shaped by evolutionary and historical forces. Therefore, genetic polymorphisms are useful tools not only to understand the susceptibility to disease in modern populations, but the history of ancestral populations as well. For this purpose, data on genetic polymorphisms such as human leucocyte antigen, mitochondrial DNA sequence variability and the frequencies of TAP1 and TAP2 gene variants in Turkey have been reported previously. Here we have used interleukin (IL)‐10 (−592C/A, −819T/C, −1082G/A) and IL‐2 (−330T/G) as genetic markers to study the relationship between Turkish population and other populations.
Bibliography:istex:7226E9D0BE5D18404632AD3B05ABFA66F13BECE2
ark:/67375/WNG-LXPJNMH4-J
ArticleID:IJI825
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1744-3121
1744-313X
DOI:10.1111/j.1744-313X.2008.00825.x