Propafenone‐induced drug fever in the absence of agranulocytosis

Propafenone is an antiarrhythmic drug used in the treatment of life‐threatening ventricular tachyarrhythmias. Adverse reactions necessitating discontinuation of the medication are common. Propafenone‐induced drug fever has not been definitively proven. We present a case report of drug fever secondar...

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Published inClinical cardiology (Mahwah, N.J.) Vol. 20; no. 7; pp. 662 - 664
Main Authors O' Rourke, Daniel J., Palac, Robert T., Holzberger, Peter T., Gerling, Barbara R., Greenberg, Mark L.
Format Journal Article
LanguageEnglish
Published New York Wiley Periodicals, Inc 01.07.1997
Subjects
Agranulocytosis - blood
Anti-Arrhythmia Agents - adverse effects
Anti-Arrhythmia Agents - therapeutic use
Diagnosis, Differential
drug fever
Fever - blood
Fever - chemically induced
Fever - diagnosis
Humans
Leukocyte Count
Male
Middle Aged
propafenone
Propafenone - adverse effects
Propafenone - therapeutic use
Tachycardia, Ventricular - drug therapy
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Summary:Propafenone is an antiarrhythmic drug used in the treatment of life‐threatening ventricular tachyarrhythmias. Adverse reactions necessitating discontinuation of the medication are common. Propafenone‐induced drug fever has not been definitively proven. We present a case report of drug fever secondary to propafenone, confirmed with rechallenge.
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.4960200715