Tuning Achiral to Chiral Supramolecular Helical Superstructures

• Published in: Chemical record Vol. 20; no. 8; pp. 793 - 819
• Main Authors: Nadimetla, Dinesh N., Al Kobaisi, Mohammad, Bugde, Sandesh T., Bhosale, Sheshanath V.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.08.2020
• Subjects: achiral; Chemical synthesis; chiral-assembly; chiral-nanostructures; Chirality; circular dichroism; electron microscopy; Handedness; Helicity; Photoluminescence; Superstructures; chiral-nanostructures; electron microscopy; circular dichroism; chiral-assembly; achiral
• ISSN: 1527-8999; 1528-0691
• DOI: 10.1002/tcr.202000004

The design and synthesis of achiral organic functional molecules which can assemble into a chiral with selective handedness in the absence of chiral substances is an important in understanding the role chirality plays within these systems. In this review, we described general approaches towards supramolecular chiral molecules the synthesis and self‐assembly of achiral molecule to active chiral molecules to investigate controlled supramolecular chiral nanostructures with their photoluminescent properties for rapid, sensitive and selective detection of analytes of choice. Various small molecules have been discussed for achiral to chiral along with induction of chirality and controlled chiral helical structures in detail. We discussed few examples where stimuli used to control the chirality such as temperature, pH etc. Finally, we will also explore on the photo responsive helicity properties of the aggregation induced emission active molecule such as tetraphenylethene conjugates. In this review, we described general approaches towards supramolecular chiral helical structures from achiral molecules via self‐assembly. This begin with introduction followed by discussion of achiral molecule to active chiral superstructures controlled by various with various stimulus is discussed. We concluded our view with future prospective in the development and utilisation of supramolecular helical structures for various applications.