Experimental evaluation of apparent tissue surface tension based on the exact solution of the Laplace equation

The notion of apparent tissue surface tension offered a systematic way to interpret certain morphogenetic processes in early development. It also allowed deducing quantitative information on cellular and molecular parameters that is otherwise difficult to obtain. To accurately determine such tension...

Full description

Saved in:
Bibliographic Details
Published inEurophysics letters Vol. 81; no. 4; pp. 46003 - pl/46003-p6
Main Authors Norotte, C, Marga, F, Neagu, A, Kosztin, I, Forgacs, G
Format Journal Article
LanguageEnglish
Published IOP Publishing 01.02.2008
EDP Sciences
Subjects
68.03.Cd
87.17.-d
Online AccessGet full text

Cover

More Information
Summary:The notion of apparent tissue surface tension offered a systematic way to interpret certain morphogenetic processes in early development. It also allowed deducing quantitative information on cellular and molecular parameters that is otherwise difficult to obtain. To accurately determine such tensions we combined novel experiments with the exact solution of the Laplace equation for the profile of a liquid drop under the employed experimental conditions and used the exact solution to evaluate data collected on tissues. Our results confirm that tissues composed of adhesive and motile cells indeed can be characterized in terms of well-defined apparent surface tension. Our experimental technique presents a way to measure liquid interfacial tensions under conditions when known methods fail.
Bibliography:istex:0868265537A3BA85BB63657BCA3DFC53034F53B8
ark:/67375/80W-M5790F6P-B
publisher-ID:epl10740
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0295-5075
1286-4854
DOI:10.1209/0295-5075/81/46003