The use of engineered protein materials in electrochemical devices

Bioelectrochemical technologies have an important and growing role in healthcare, with applications in sensing and diagnostics, as well as the potential to be used as implantable power sources and be integrated with automated drug delivery systems. Challenges associated with enzyme-based electrodes...

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Bibliographic Details
Published inExperimental biology and medicine (Maywood, N.J.) Vol. 241; no. 9; pp. 980 - 985
Main Authors Renner, Julie N, Minteer, Shelley D
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.05.2016
Subjects
Electrochemical Techniques - instrumentation
Electrodes
Equipment Design
Minireview
Protein Engineering - methods
Proteins - chemistry
enzymatic biofuel cell
Protein engineering
biocatalysts
electrochemical biosensors
bioelectrocatalysis
bioelectrodes
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Summary:Bioelectrochemical technologies have an important and growing role in healthcare, with applications in sensing and diagnostics, as well as the potential to be used as implantable power sources and be integrated with automated drug delivery systems. Challenges associated with enzyme-based electrodes include low current density and short functional lifetimes. Protein engineering is emerging as a powerful tool to overcome these issues. By taking advantage of the ability to precisely define protein sequences, electrodes can be organized into high performing structures, and enable the next generation of medical devices.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1535-3702
1535-3699
DOI:10.1177/1535370216647127