Carboxymethyl cellulose-based materials for infection control and wound healing: A review

The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biode...

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Bibliographic Details
Published inInternational journal of biological macromolecules Vol. 164; pp. 963 - 975
Main Authors Kanikireddy, Vimala, Varaprasad, Kokkarachedu, Jayaramudu, Tippabattini, Karthikeyan, Chandrasekaran, Sadiku, Rotimi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.12.2020
Subjects
Animals
Antimicrobial
Bandages
Biocompatible Materials - chemistry
Biomedical
Carboxymethyl cellulose
Carboxymethylcellulose Sodium - chemistry
Cellulose
Humans
Hydrogels - chemistry
Infection Control
Mice
Nanoparticles - chemistry
Polymers - chemistry
Printing, Three-Dimensional
Ulcer
Wound dressing
Wound Healing
Carboxymethyl cellulose
Antimicrobial
Wound dressing
Biomedical
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Summary:The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing. [Display omitted] •CMC utilization for the preparation of wound dressing materials is reviewed.•The wound healing process of antibiotic-loaded CMC wound dressing materials is discussed.•The review presents various types of CMC-based wound healing materials.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2020.07.160