Chemical gelling of hydrogels-based biological macromolecules for tissue engineering: Photo- and enzymatic-crosslinking methods

• Published in: International journal of biological macromolecules Vol. 139; pp. 760 - 772
• Main Authors: Nezhad-Mokhtari, Parinaz, Ghorbani, Marjan, Roshangar, Leila, Soleimani Rad, Jafar
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.10.2019
• Subjects: Animals; Biocompatible Materials - chemistry; Catalysis; Cell Culture Techniques; Cell Survival; Chondrocytes - cytology; Collagen - chemistry; Cross-Linking Reagents - chemistry; Drug Combinations; Enzymatically-crosslinking; Enzymes - chemistry; Humans; Hydrogels; Hydrogels - administration & dosage; Hydrogels - chemistry; Injections; Laminin - chemistry; Mice; NIH 3T3 Cells; Osteoblasts - cytology; Photochemically cross-linking; Photochemistry - methods; Polymers - chemistry; Proteoglycans - chemistry; Tissue engineering; Tissue Engineering - methods; Hydrogels; Tissue engineering; Photochemically cross-linking; Enzymatically-crosslinking

Newly, injectable hydrogels have been renowned as promising biomaterials and appropriate candidates for tissue engineering which can be applied for the development of 3-dimensional cell culture models. Hydrogels have in situ formability that allows an actual and homogeneous drugs/cells encapsulation...