TACCing down the spindle poles

Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and indicate that a conserved protein complex may be critical to the stability of both the astral...

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Bibliographic Details
Published inNature cell biology Vol. 3; no. 7; pp. E159 - E161
Main Author Theurkauf, William E
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 01.07.2001
Subjects
Animals
Drosophila melanogaster - ultrastructure
Drosophila Proteins
Female
Gene mutations
Genetic aspects
Insect Proteins - pharmacology
Kinesin - physiology
Microtubule-Associated Proteins - metabolism
Microtubule-Associated Proteins - pharmacology
Microtubule-Associated Proteins - physiology
Microtubules
Physiological aspects
Spindle (Cell division)
Spindle Apparatus - drug effects
Spindle Apparatus - metabolism
Spindle Apparatus - ultrastructure
United States
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Summary:Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and indicate that a conserved protein complex may be critical to the stability of both the astral- and anastral-spindle pole.
Bibliography:SourceType-Other Sources-1
ObjectType-News-1
ObjectType-Commentary-2
content type line 66
ISSN:1465-7392
1476-4679
DOI:10.1038/35083110