Continuous-Flow Left Ventricular Assist Device-Related Gastrointestinal Bleeding

Continuous-flow (CF) left ventricular assist devices (LVADs) are a safe and durable therapeutic option for patients with advanced heart failure as a bridge to transplant or as destination therapy. Despite the remarkable technological advances in device design and increasing familiarity with the phys...

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Bibliographic Details
Published inCardiology clinics Vol. 36; no. 4; p. 519
Main Authors Kim, Ju H, Brophy, Donald F, Shah, Keyur B
Format Journal Article
LanguageEnglish
Published Netherlands 01.11.2018
Subjects
Gastrointestinal Hemorrhage - etiology
Heart Failure - surgery
Heart-Assist Devices - adverse effects
Humans
Postoperative Hemorrhage - etiology
Left ventricular assist device
Gastrointestinal bleed
Octreotide
Angiodysplasia
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Summary:Continuous-flow (CF) left ventricular assist devices (LVADs) are a safe and durable therapeutic option for patients with advanced heart failure as a bridge to transplant or as destination therapy. Despite the remarkable technological advances in device design and increasing familiarity with the physiologic effects of CF, major complications such as gastrointestinal bleeding (GIB) continue to cause significant morbidity. The causes underlying CF-LVAD-related GIB are multifactorial. Accordingly, management strategies for CF-LVAD-related GIB encompass a wide range of therapeutic modalities. This article reviews the epidemiology, pathophysiology, risk factors, and treatment options for the management of this complex complication.
ISSN:1558-2264
DOI:10.1016/j.ccl.2018.06.006