Differences in vascular response between primary and transplanted tumours

• Published in: British journal of cancer Vol. 63; no. 5; pp. 723 - 726
• Main Authors: FIELD, S. B, NEEDHAM, S, BURNEY, I. A, MAXWELL, R. J, COGGLE, J. E, GRIFFITHS, J. R
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.05.1991
• Subjects: Animal tumors. Experimental tumors; Animals; Biological and medical sciences; Experimental tumors, general aspects; Fibroma - blood supply; Fibrosarcoma - blood supply; Histiocytoma, Benign Fibrous - blood supply; Hydralazine - pharmacology; Magnetic Resonance Spectroscopy; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Radiation-Induced - blood supply; Phosphorus; Regional Blood Flow - drug effects; Skin Neoplasms - blood supply; Skin Neoplasms - etiology; Tumors; Vertebrata; Mammalia; Mouse; Animal; Rodentia; Primary; Tumor; NMR spectrometry; Homotransplantation; Vascularization

The vast majority of studies on tumour vasculature are performed on transplanted tumours in rodents. However, it is known that there may be differences between primary and transplanted lesions. The purpose of this study is to test whether a specific vascular response is similar in primary tumours an...