Synthesis of sulfones via selective C-H-functionalization
The synthesis of sulfones via a selective functionalization of C-H-bonds represents a powerful alternative to classical methods for the preparation of this important compound class. Within the last decade, significant progress has been made in this field. This review highlights recent advances in th...
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| Published in | Organic & biomolecular chemistry Vol. 15; no. 9; pp. 1947 - 1955 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.03.2017
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| Subjects | |
| Online Access | Get full text |
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| Summary: | The synthesis of sulfones
via
a selective functionalization of C-H-bonds represents a powerful alternative to classical methods for the preparation of this important compound class. Within the last decade, significant progress has been made in this field. This review highlights recent advances in the area of metal-catalyzed as well as metal-free transformations for the direct sulfonylation of C(sp
2
)-H and C(sp
3
)-H bonds.
This review highlights recent advances in the synthesis of sulfones
via
the selective functionalization of C-H-bonds. |
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| Bibliography: | Nai-Wei Liu was born in Taipei (Taiwan R.O.C.). He studied chemistry at the Goethe-University Frankfurt and joined the group of Georg Manolikakes for his PhD thesis in 2014. He is currently on the development of new methods for the fixation of sulfur dioxide into small molecules. cancer, neurodegenerative diseases) using multicomponent and one-pot reactions. Shuai Liang was born in Qingdao (China). He earned his BS degree in 2011 from Sichuan University. In 2014 he received his MS degree in chemistry from Sichuan University under the supervision of Prof. Xiaoqi Yu. Since November 2014 he is a PhD student at the Goethe University. His current research interest focuses on novel methods for the synthesis of sulfones Georg Manolikakes was born in Ebersberg (Germany). He studied chemistry at the LMU Munich. In 2009 he obtained his PhD from the same university under the guidance of Paul Knochel, working on functionalized organometallics and cross-coupling reactions. From 2009-2010 he worked as a postdoctoral fellow with Phil S. Baran at the Scripps Research Institute on synthesis of cortistatin A. Since 2010 he is a junior research group leader at the Goethe-University Frankfurt. His research interests are multicomponent and one-pot-reactions, the synthesis of sulfonyl-group-containing molecules and asymmetric synthesis. selective C-H-functionalization. Saad Shaaban obtained his PhD in 2011 from the School of Pharmacy, Saarland University, Germany. He worked as a postdoctoral researcher at the Doemling's Drug Design group, Groningen University, The Netherlands; the Wessjohann's Bioorganic Chemistry group, Leibniz Institute of Plant Biochemistry, Germany and the BioPeroxIL group, University of Bourgogne, France. In the end of 2016, he joined the Manolikakes group at the Goethe-Universität Frankfurt. Dr Shaaban's long term vision is to bring novel drug to patients in an indicated area of unmet medical needs e.g. via ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2 |
| ISSN: | 1477-0520 1477-0539 |
| DOI: | 10.1039/c6ob02424f |