SERS nanoprobes for bio-application

The ability to tune the size, shape, composition and surface properties impart nanoparticles with the desired functions for bio-application. This article highlights some of the recent examples in the exploration of metal (e.g., gold and silver) nanoparticles, especially those with magnetic propertie...

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Bibliographic Details
Published inFrontiers of chemical science and engineering Vol. 9; no. 4; pp. 428 - 441
Main Authors Cheng, Han-Wen, Luo, Jin, Zhong, Chuan-Jian
Format Journal Article
LanguageEnglish
Published Beijing Higher Education Press 01.12.2015
Subjects
Chemistry
Chemistry and Materials Science
Industrial Chemistry/Chemical Engineering
Nanotechnology
Review Article
theranostic materials
bio-conjugation
functional nanoprobes
magnetic properties
metal nanoparticles
surface-enhanced Raman scattering
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Summary:The ability to tune the size, shape, composition and surface properties impart nanoparticles with the desired functions for bio-application. This article highlights some of the recent examples in the exploration of metal (e.g., gold and silver) nanoparticles, especially those with magnetic properties and bio-conjugated structures, as theranostic nanoprobes. Such nanoprobes exhibit tunable optical, spectroscopic, magnetic, and electrical properties for signal amplifications. Examples discussed in this article will focus on the nanoproble-enhanced colorimetric detection and surface enhanced Raman scattering (SERS) detection of biomarkers or biomolecules such as proteins and DNAs. The understanding of factors controlling the biomolecular interactions is essential for the design of SERS nanoprobes with theranostic functions.
ISSN:2095-0179
2095-0187
DOI:10.1007/s11705-015-1536-0