PDMS-based microfluidic devices for biomedical applications

Microfluidic devices provide a number of advantageous features for microscale biochemical systems for analysis and/or synthesis. A PDMS (polydimethylsiloxane) microchip, for instance, which has microchannels for electrophoretic separation can be easily fabricated through a molding process. Sealing o...

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Bibliographic Details
Published inMicroelectronic engineering Vol. 61; pp. 907 - 914
Main Author Fujii, Teruo
Format Journal Article Conference Proceeding
LanguageEnglish
Published Amsterdam Elsevier B.V 01.07.2002
Elsevier Science
Subjects
Analytical biochemistry: general aspects, technics, instrumentation
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Lab-on-a-chip
Micro-TAS
Microfluidics
PDMS
Micro-TAS
Lab-on-a-chip
Microfluidics
PDMS
Biomedical electronics
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Summary:Microfluidic devices provide a number of advantageous features for microscale biochemical systems for analysis and/or synthesis. A PDMS (polydimethylsiloxane) microchip, for instance, which has microchannels for electrophoretic separation can be easily fabricated through a molding process. Sealing of those channels does not need any elaborate bonding processes which are usually required for glass chips. We have been working on PDMS-based microfluidic devices for biomedical applications, where microreactors, microchips for capillary gel electrophoresis, and hydrophobic vent valves are successfully fabricated and operated. Fundamentals of PDMS-based microfluidic devices and their functions are described as well as the experimental results.
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ISSN:0167-9317
1873-5568
DOI:10.1016/S0167-9317(02)00494-X