Acute Percutaneous Lactic Acid Poisoning in a Child

• Published in: Pediatric dermatology Vol. 23; no. 3; pp. 282 - 285
• Main Authors: Ramírez, Manuela Esteban, Youseef, Wael Fasheh, Romero, Roser Garrido, Martínez, José María Quintillá, González-Enseñat, Maria Antonia, Vilaplana, Xavier Sanmartí, Cubells, Carles Luaces
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.05.2006; Blackwell
• Subjects: Acidosis, Lactic - chemically induced; Acidosis, Lactic - diagnosis; Acidosis, Lactic - therapy; Administration, Cutaneous; Biological and medical sciences; Dermatology; Female; Humans; Ichthyosis, Lamellar - drug therapy; Infant; Lactic Acid - administration & dosage; Lactic Acid - poisoning; Medical sciences; Human; Pediatrics; Hydroxyacid; Dermatology; Acute; Poisoning; Lactic acid; Child; Percutaneous route
• ISSN: 0736-8046; 1525-1470
• DOI: 10.1111/j.1525-1470.2006.00236.x

:  Percutaneous poisoning is quite rare, and in particular, topical lactic acid poisoning is even more so. We report a young girl with lamellar ichthyosis and symptoms of poisoning, with clinical signs of irritability, agitation, myoclonia, and difficulty in walking, accompanied by lactic acidosis as a result of the more frequent than recommended application of emollients containing lactic acid. The clinical symptoms resolved upon discontinuation of the topical treatment. Among the possible causes of metabolic acidosis, health care providers should be aware of the possibility of percutaneous poisoning.