An evaluation of algorithms designed to classify the results from frequency doubling perimetry

• Published in: Ophthalmic & physiological optics Vol. 24; no. 6; pp. 498 - 503
• Main Authors: Müskens, Rogier P. H. M., Heeg, Govert P., Jansonius, Nomdo M.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.11.2004; Blackwell
• Subjects: Aged; Aged, 80 and over; Algorithms; Biological and medical sciences; Female; frequency doubling perimetry; glaucoma; Glaucoma - diagnosis; Glaucoma - physiopathology; Humans; Investigative techniques of ocular function and vision; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; perimetry; receiver-operating characteristic curve; ROC Curve; sensitivity; Sensitivity and Specificity; Sensory Thresholds; specificity; Visual Field Tests - methods; Visual Fields; Design; Evaluation; Frequency; Ophthalmology; Perimetry; Algorithm
• ISSN: 0275-5408; 1475-1313
• DOI: 10.1111/j.1475-1313.2004.00224.x

All previously published algorithms for the interpretation of frequency doubling perimetry test results were compared in full‐threshold mode in a large group of glaucoma patients (n = 452) and normal subjects (n = 237). Areas under the receiver–operating characteristic (ROC) curve ranged from 0.86 to 0.92. None of the algorithms performed substantially better than simply counting the number of defects p < 1% in the total deviation plot. For this algorithm, we found a sensitivity of 0.90 and a specificity of 0.81 at a cut‐off point of >1 defect, and an area under the ROC curve of 0.92.