Multimeric, Multifunctional Derivatives of Poly(ethylene glycol)

This article reviews the use of multifunctional polymers founded on high-molecular weight poly(ethylene glycol) (PEG). The design of new PEG derivatives assembled in a dendrimer-like multimeric fashion or bearing different functionalities on the same molecule is described. Their use as new drug deli...

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Bibliographic Details
Published inPolymers Vol. 3; no. 3; pp. 1076 - 1090
Main Authors Zacchigna, Marina, Cateni, Francesca, Drioli, Sara, Bonora, Gian Maria
Format Journal Article Book Review
LanguageEnglish
Published Basel MDPI AG 01.09.2011
Subjects
conjugation
drug delivery
multifunctional polymers
poly(ethylene glycol)
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Summary:This article reviews the use of multifunctional polymers founded on high-molecular weight poly(ethylene glycol) (PEG). The design of new PEG derivatives assembled in a dendrimer-like multimeric fashion or bearing different functionalities on the same molecule is described. Their use as new drug delivery systems based on the conjugation of multiple copies or diversely active drugs on the same biocompatible support is illustrated.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym3031076