Case report: COVID-19-associated mucormycosis co-infection with Lomentospora prolificans : The first case and review on multiple fungal co-infections during COVID-19 pandemic

Along with the pandemic COVID-19 spreads, new clinical challenges have emerged in the health care settings, among which there is a high risk of secondary invasive fungal infections with significant mortality. Here, we report a case of invasive fungal rhino orbital sinusitis due to the simultaneous c...

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Published inFrontiers in medicine Vol. 10; p. 1078970
Main Authors Erami, Mahzad, Mirhendi, Hossein, Momen-Heravi, Mansooreh, Sharif, Alireza, Hashemi Hezaveh, Seyed Jamal, Matini, Amir Hassan, Ahsaniarani, Amir Hossein, Aboutalebian, Shima
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 16.03.2023
Subjects
antifungal susceptibility testing
COVID-19
Lomentospora prolificans
Medicine
mucormycosis
multiple co-infection
COVID-19
Lomentospora prolificans
multiple co-infection
antifungal susceptibility testing
mucormycosis
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Summary:Along with the pandemic COVID-19 spreads, new clinical challenges have emerged in the health care settings, among which there is a high risk of secondary invasive fungal infections with significant mortality. Here, we report a case of invasive fungal rhino orbital sinusitis due to the simultaneous co-infection by and , both identified by sequencing, in a 70-year-old Afghanistanian female with COVID-19. The patient was subjected to surgical debridement as well as taking liposomal amphotericin B, voriconazole, and on discharge, her condition was good. As far as we know, this is the first case of co-infection of COVID-19-associated mucormycosis (CAM) and infection. Multiple fungal co-infections in COVID-19 patients are reviewed.
Bibliography:Reviewed by: Hector M. Mora-Montes, Universidad de Guanajuato, Mexico; Santosh Kumar Swain, Siksha ‘O’ Anusandhan University, India; Valliappan Muthu, Postgraduate Institute of Medical Education and Research (PGIMER), India
This article was submitted to Infectious Diseases: Pathogenesis and Therapy, a section of the journal Frontiers in Medicine
ORCID: Shima Aboutalebian, https://orcid.org/0000-0003-0178-4372
Edited by: Shisan (Bob) Bao, The University of Sydney, Australia
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2023.1078970