Clinical correlation of high activity dynamic hepatic scintigraphy in patients with colorectal cancer

• Published in: British journal of cancer Vol. 65; no. 5; pp. 781 - 782
• Main Authors: HEMINGWAY, D. M, COOKE, T. G, MCCURRACH, G, BESSENT, R. G, CARTER, R, MCKILLOP, J. H, MCARDLE, C. S
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.05.1992
• Subjects: Biological and medical sciences; Colorectal Neoplasms - diagnostic imaging; Colorectal Neoplasms - pathology; Digestion. Liver. Biliary tract. Spleen. Pancreas; Hepatic Artery - physiology; Humans; Investigative techniques, diagnostic techniques (general aspects); Liver - blood supply; Liver - diagnostic imaging; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - secondary; Medical sciences; Neoplasm Metastasis - diagnosis; Perfusion; Pilot Projects; Predictive Value of Tests; Radionuclide Imaging; Radionuclide investigations; Sensitivity and Specificity; Technetium Tc 99m Aggregated Albumin; Hepatic artery; Radionuclide study; Human; Liver; Hepatic disease; Metastasis; Scintigraphy; Malignant tumor; Blood; Blood flow; Rectum; Digestive diseases; Complication; Intestinal disease; Colon; Hemodynamics
• ISSN: 0007-0920; 1532-1827
• DOI: 10.1038/bjc.1992.166

The hepatic perfusion index, the ratio of hepatic arterial to total liver blood flow, was measured in 50 consecutive patients with colorectal cancer using radiolabelled colloid with high administered activity. In patients with proven liver metastases the diagnostic sensitivity of the HPI was 96% and the predictive value of a negative test was 92%. Dynamic hepatic scintigraphy is of value in the management of patients with colorectal cancer.