Unravelling spiral cleavage

Snails, earthworms and flatworms are remarkably different animals, but they all exhibit a very similar mode of early embryogenesis: spiral cleavage. This is one of the most widespread developmental programs in animals, probably ancestral to almost half of the animal phyla, and therefore its study is...

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Bibliographic Details
Published inDevelopment (Cambridge) Vol. 147; no. 1
Main Authors Martín-Durán, José M, Marlétaz, Ferdinand
Format Journal Article
LanguageEnglish
Published England 02.01.2020
Subjects
Emerging model systems
Cell lineages
Phylogeny
Developmental plasticity
Spiral cleavage
Cell fates
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Summary:Snails, earthworms and flatworms are remarkably different animals, but they all exhibit a very similar mode of early embryogenesis: spiral cleavage. This is one of the most widespread developmental programs in animals, probably ancestral to almost half of the animal phyla, and therefore its study is essential for understanding animal development and evolution. However, our knowledge of spiral cleavage is still in its infancy. Recent technical and conceptual advances, such as the establishment of genome editing and improved phylogenetic resolution, are paving the way for a fresher and deeper look into this fascinating early cleavage mode.
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ISSN:0950-1991
1477-9129
DOI:10.1242/dev.181081