Patterns of reactivity of the monoclonal antibody 791T/36 with different tumour metastases in the liver

• Published in: British journal of cancer Vol. 54; no. 6; pp. 871 - 875
• Main Authors: HAWKEY, C. J, HOLMES, C. H, SMITH, P. G, AUSTIN, E. B, BALDWIN, R. W
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.12.1986
• Subjects: Adenocarcinoma - immunology; Adult; Aged; Antibodies, Monoclonal - immunology; Biological and medical sciences; Bronchial Neoplasms - immunology; Carcinoma, Small Cell - immunology; Colonic Neoplasms - immunology; Female; Gastroenterology. Liver. Pancreas. Abdomen; Hodgkin Disease - immunology; Humans; Immunoenzyme Techniques; Liver - immunology; Liver Neoplasms - immunology; Liver Neoplasms - secondary; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; Pancreatic Neoplasms - immunology; Rectal Neoplasms - immunology; Thyroid Neoplasms - immunology; Tumors; Human; Reactivity; Immunological investigation; Liver; Digestive diseases; Tumor; Metastatic; Monoclonal antibody

Reactivity of the monoclonal antibody 791T/36 with secondary malignant deposits has been investigated in frozen sections of 74 human liver biopsy specimens. There was no reactivity with hepatocytes but in some instances binding to fibrous tissues and in one case to portal tract lymphocytes was obser...