A Review of Particle Therapy for Skull Base Tumors: Modern Considerations and Future Directions

Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review...

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Published inInternational journal of particle therapy Vol. 8; no. 1; pp. 168 - 178
Main Authors Hug, Eugen B., Pelak, Maciej, Frank, Steven J., Fossati, Piero
Format Journal Article
LanguageEnglish
Published The Particle Therapy Co-operative Group 01.06.2021
Elsevier
Subjects
carbon ion therapy
chordoma
Clinical
particle therapy
proton beam therapy
skull base tumors
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Summary:Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.
Bibliography:ObjectType-Article-1
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ISSN:2331-5180
2331-5180
DOI:10.14338/IJPT-20-00083