Endocrinology of Adipose Tissue - An Update

Abstract Adipose tissue is the body's largest repository of energy and it plays an important role in total energy homeostasis. Moreover, it is now well recognized as an endocrine organ. A wide range of different factors including complex proteins as well as fatty acids, prostaglandins, and ster...

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Bibliographic Details
Published inHormone and metabolic research Vol. 39; no. 5; pp. 314 - 321
Main Authors Fischer-Posovszky, P., Wabitsch, M., Hochberg, Z.
Format Journal Article
LanguageEnglish
Published Germany 01.05.2007
Subjects
Adipocytes - physiology
Adipose Tissue - physiology
Animals
Cytokines - physiology
Endocrine System - physiology
Hormones - physiology
Humans
Special Topics Revisited
adiponectin
RBP-4
adipocyte
SGBS cells
leptin
obesity
fat cell
visfatin
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ISSN0018-5043
1439-4286
DOI10.1055/s-2007-976539

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Summary:Abstract Adipose tissue is the body's largest repository of energy and it plays an important role in total energy homeostasis. Moreover, it is now well recognized as an endocrine organ. A wide range of different factors including complex proteins as well as fatty acids, prostaglandins, and steroids are either synthesized DE NOVO or converted in adipose tissue and released into the blood stream. These so-called adipokines contribute to the development of obesity-related disorders, particularly type-2 diabetes (T2D) and cardiovascular disease. In this review, we present an overview on the endocrine functions of adipose tissue with a special focus on discoveries reported within the past 5 years.
ISSN:0018-5043
1439-4286
DOI:10.1055/s-2007-976539