Toxicological data after heroin overdose

Capillary gas chromatography with selective nitrogen detection was employed to quantify morphine and 6-monoacetylmorphine in biological fluids and tissues in five deaths attributed to heroin injection overdose. The minimum lethal concentration found was 0.021 micrograms morphine per ml of blood. In...

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Bibliographic Details
Published inHuman & experimental toxicology Vol. 8; no. 6; pp. 487 - 489
Main Authors Kintz, P, Mangin, P, Lugnier, A A, Chaumont, A J
Format Journal Article
LanguageEnglish
Published England 01.11.1989
Subjects
Adult
Chromatography, Gas
Heroin - metabolism
Heroin - pharmacokinetics
Heroin - poisoning
Humans
Male
Morphine - pharmacokinetics
Morphine - urine
Morphine Derivatives - urine
Tissue Distribution
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Summary:Capillary gas chromatography with selective nitrogen detection was employed to quantify morphine and 6-monoacetylmorphine in biological fluids and tissues in five deaths attributed to heroin injection overdose. The minimum lethal concentration found was 0.021 micrograms morphine per ml of blood. In all cases, 6-monoacetylmorphine was identified in urine, confirming heroin abuse.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0144-5952
0960-3271
DOI:10.1177/096032718900800609