Mortality in ischemic stroke score: A predictive score of mortality for acute ischemic stroke

• Published in: Brain circulation Vol. 3; no. 1; pp. 29 - 34
• Main Authors: Mittal, Saumya H, Goel, Deepak
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.01.2017; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Analysis; Blood flow; Diabetes; Epidemiology; Fatalities; Hematology; Hemorrhage; Hospitals; Hyperglycemia; Medicare; Mortality; mortality in ischemic stroke score system; mortality in stroke; mortality score; Neurology; Original; Patient outcomes; Patients; Stroke; Stroke (Disease); stroke severity; stroke-related death; United States > US; India; mortality in stroke; Mortality in ischemic stroke score system; mortality score; stroke-related death; stroke severity
• ISSN: 2394-8108; 2455-4626; 2455-4626
• DOI: 10.4103/2394-8108.203256

This prospective study was planned to formulate and evaluate a predictive score for in-hospital mortality in cases of acute ischemic stroke. In this study, 188 consecutive patients of ischemic stroke were included over 19 months. Only patients with renal failure and malignancy were excluded from the study. All patients were subjected to clinical evaluation along with Glasgow Coma Scale (GCS), National Institute of Health Science scale (NIHSS) score, and modified Rankin score (mRS). Investigations total leukocyte count (TLC), capillary blood sugar at admission, high-sensitivity C-reactive protein (HS-CRP), and troponin I, electrocardiogram, and neuroimaging were performed. The patients were followed up till their outcome in the hospital, and patients who expired were grouped as "mortality group" and the rest as "discharged group." One-way anova analysis was carried out among the significant parameters to identify independent predictors of mortality in cases of ischemic stroke. After statistical analysis, it was found that late presentation to the hospital, pyrexia (temperature >99F), low diastolic blood pressure at the time of admission, hypoxia (saturation of oxygen <94%), NIHSS score >15, mRS >3, GCS <8, hyperglycemia (random blood sugar >200 mg/dL), raised TLC, and HS-CRP (>10 mg/L) are positive predictive factors of mortality in cases of ischemic stroke. Based on the above findings, a simple and easily applicable mortality in ischemic stroke (MIS) score is developed. This MIS score system will help the clinicians in better management of the patient and improved counseling the relatives of patients with ischemic stroke.