Role of Active Surveillance in the Management of Localized Prostate Cancer

Active surveillance is an increasingly recognized treatment option for men with low-risk prostate cancer. Despite encouraging evidence for oncologic efficacy and reduction in morbidity, several barriers contribute to the underuse of this management strategy. Consistent selection criteria as well as...

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Bibliographic Details
Published inJournal of the National Cancer Institute. Monographs Vol. 2012; no. 45; pp. 202 - 206
Main Authors Glass, Allison S., Cooperberg, Matthew R., Meng, Maxwell V., Carroll, Peter R.
Format Journal Article
LanguageEnglish
Published US Oxford University Press 01.12.2012
Subjects
Biomarkers, Tumor
Disease Management
Disease Progression
Early Detection of Cancer
Humans
Male
Neoplasm Grading
Prognosis
Prostate-Specific Antigen - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Risk
Watchful Waiting
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Summary:Active surveillance is an increasingly recognized treatment option for men with low-risk prostate cancer. Despite encouraging evidence for oncologic efficacy and reduction in morbidity, several barriers contribute to the underuse of this management strategy. Consistent selection criteria as well as identification and validation of triggers for subsequent intervention are essential. Incorporation of novel biomarkers as well as advanced imaging techniques may improve surveillance strategies by better defining eligibility as well as improving prompt detection of disease progression.
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ISSN:1052-6773
1745-6614
DOI:10.1093/jncimonographs/lgs032