Peyronie's disease: a review

We provide a current review of Peyronie's disease. We reviewed the world peer reviewed literature on the pathology, pathogenesis, diagnosis and treatment of Peyronie's disease. The incidence of Peyronie's disease has continuously increased during the last 30 years. However, fewer pati...

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Bibliographic Details
Published inThe Journal of urology Vol. 169; no. 4; p. 1234
Main Authors Gholami, Shahram S, Gonzalez-Cadavid, Nestor F, Lin, Ching-Shwu, Rajfer, Jacob, Lue, Tom F
Format Journal Article
LanguageEnglish
Published United States 01.04.2003
Subjects
Cell Differentiation - genetics
Cell Division - genetics
Fibroblasts - pathology
Gene Expression Regulation - physiology
Humans
Male
Myostatin
Oligonucleotide Array Sequence Analysis
Penile Induration - genetics
Penile Induration - pathology
Penile Induration - therapy
Penis - pathology
Reactive Oxygen Species - metabolism
Transforming Growth Factor beta - genetics
Transforming Growth Factor beta1
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Summary:We provide a current review of Peyronie's disease. We reviewed the world peer reviewed literature on the pathology, pathogenesis, diagnosis and treatment of Peyronie's disease. The incidence of Peyronie's disease has continuously increased during the last 30 years. However, fewer patients need prosthesis surgery as the sole treatment option because of earlier diagnosis, improved medical therapy, refinement in surgical technique and better understanding of the basic sciences of the disease. Currently patients with Peyronie's disease have had improvements in prognosis and experienced an expansion of the available therapeutic options.
ISSN:0022-5347
DOI:10.1097/01.ju.0000053800.62741.fe