Supramolecular fluorogenic peptide sensor array based on graphene oxide for the differential sensing of ebola virus

We report on a supramolecular sensor array using fluorogenic peptide probes and graphene oxide that can target glycoproteins on a viral caspid, facilitating the differentiation of ebola virus from marburg virus and receptor-extensive vesicular stomatitis virus using principal component analysis. Pri...

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Published inChemical communications (Cambridge, England) Vol. 56; no. 43; pp. 5735 - 5738
Main Authors Fu, Meng-Qi, Wang, Xu-Chen, Dou, Wei-Tao, Chen, Guo-Rong, James, Tony D, Zhou, Dong-Ming, He, Xiao-Peng
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 28.05.2020
Subjects
Biosensing Techniques
Capsid Proteins - chemistry
chemical reactions
Ebola virus
Ebolavirus
Ebolavirus - isolation & purification
Fluorescent Dyes - chemistry
Glycoproteins
Glycoproteins - chemistry
Graphene
graphene oxide
Graphite - chemistry
Marburg marburgvirus
Marburgvirus - isolation & purification
Peptides
Peptides - chemistry
principal component analysis
Principal components analysis
Sensor arrays
Vesiculovirus
Vesiculovirus - isolation & purification
Viral diseases
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Summary:We report on a supramolecular sensor array using fluorogenic peptide probes and graphene oxide that can target glycoproteins on a viral caspid, facilitating the differentiation of ebola virus from marburg virus and receptor-extensive vesicular stomatitis virus using principal component analysis. Principal component analysis of a fluorescent supramolecular sensor array based on graphene oxide can be used to differentiate ebola virus from marburg virus and receptor-extensive vesicular stomatitis virus.
Bibliography:Electronic supplementary information (ESI) available: Experimental details associated with this research. See DOI
10.1039/c9cc09981f
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SourceType-Scholarly Journals-1
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/c9cc09981f