Antihyperlipidemic effects of buckwheat leaf and flower in rats fed a high-fat diet

• Published in: Food chemistry Vol. 119; no. 1; pp. 235 - 240
• Main Authors: Lee, Jeong-Sun, Bok, Song-Hae, Jeon, Seon-Min, Kim, Hye-Jin, Do, Kyung-Min, Park, Yong-Bok, Choi, Myung-Sook
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.03.2010; [Amsterdam]: Elsevier Science; Elsevier
• Subjects: Adipose tissue; animal models; antilipemic agents; Biological and medical sciences; blood lipids; buckwheat; Buckwheat leaf and flower; Cereal and baking product industries; cholesterol; dietary fiber; excretion; Fagopyrum esculentum; feces; Feeding. Feeding behavior; flowers; Food industries; Fundamental and applied biological sciences. Psychology; grain crops; High-fat diet; hyperlipidemia; Hypolipidemic effect; leaves; lipemic effect; liver; medicinal plants; phenolic compounds; protective effect; rats; sterols; synergism; triacylglycerols; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Adipose tissue; Hypolipidemic effect; High-fat diet; Buckwheat leaf and flower; Flower; Rat; Rodentia; Buckwheat; Plant leaf; Vertebrata; Mammalia; Plant part; Diet; Pseudocereals; Fat
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2009.06.014

This study was conducted to investigate the hypolipidemic effects of a powdered whole buckwheat leaf and flower mixture in rats fed a high-fat diet. Male Sprague–Dawley rats were divided into three groups: normal control (NC), high-fat (HF), and high-fat supplemented with a mixture of powdered buckwheat leaf and flower (BLF; 5%, wt/wt) groups. The plasma total cholesterol and triglyceride concentrations were significantly lower in the BLF group than in the other groups. Hepatic cholesterol and triglyceride values of the BLF group were similar to those of the NC group. This plant part mixture elevated the faecal triglyceride and acidic sterol level in the BLF group. The result suggest that the beneficial effect of this buckwheat plant portion on plasma and hepatic lipid profiles in high-fat fed rats is partly mediated by higher excretion of faecal lipids and synergistic effect of phenolic compounds and fibre present in the BLF.