The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis

To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies. We searched Ovid Medline, Ovid Embase and Ovid PsycINFO from inception to December 2020. We included studies of the prevalence of anxiety sympt...

Full description

Saved in:
Bibliographic Details
Published inGeneral hospital psychiatry Vol. 72; pp. 131 - 140
Main Authors Walker, Jane, van Niekerk, Maike, Hobbs, Harriet, Toynbee, Mark, Magill, Nicholas, Bold, Rhian, Hampsey, Elliot, Harriss, Eli, Frost, Chris, Sharpe, Michael
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.2021
Subjects
Anxiety
Anxiety - epidemiology
Anxiety Disorders - epidemiology
General hospital inpatient
Hospitals, General
Humans
Inpatients
Meta-analysis
Prevalence
Systematic review
Systematic review
Anxiety
Prevalence
General hospital inpatient
Meta-analysis
Online AccessGet full text

Cover

More Information
Summary:To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies. We searched Ovid Medline, Ovid Embase and Ovid PsycINFO from inception to December 2020. We included studies of the prevalence of anxiety symptoms of clinically significant severity (using cut-off scores on rating scales) and of the prevalence of anxiety disorders (using diagnostic interviews) in general hospital inpatients. Two independent reviewers assessed articles and extracted data. The review is registered with PROSPERO, number CRD42020189722. We included 32 studies. Pooled prevalence estimates in random-effects meta-analyses were: anxiety symptoms 28% (95% CI 19% to 38%, 95% prediction interval 5% to 72%), any anxiety disorder 8% (95% CI 5% to 12%, 95% prediction interval 2% to 33%), panic disorder 3% (95% CI 2% to 4%, 95% prediction interval 1% to 8%), generalized anxiety disorder 5% (95% CI 3% to 8%, 95% prediction interval 1% to 23%). There was high heterogeneity in prevalence, little of which was explained in exploratory analyses of a limited number of potential determinants. Anxiety symptoms of clinically significant severity affect more than one in four inpatients and anxiety disorders affect nearly one in ten.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Undefined-3
ISSN:0163-8343
1873-7714
DOI:10.1016/j.genhosppsych.2021.08.004