Recent advances in the management of multiple myeloma: clinical impact based on resource-stratification. Consensus statement of the Asian Myeloma Network at the 16th international myeloma workshop

• Published in: Leukemia & lymphoma Vol. 59; no. 10; pp. 2305 - 2317
• Main Authors: Tan, Daryl, Lee, Jae Hoon, Chen, Wenming, Shimizu, Kazuyuki, Hou, Jian, Suzuki, Kenshi, Nawarawong, Weerasak, Huang, Shang-Yi, Sang Chim, Chor, Kim, Kihyun, Kumar, Lalit, Malhotra, Pankaj, Chng, Wee Joo, Durie, Brian
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 03.10.2018
• Subjects: Myeloma; novel agents; resource-stratified; Myeloma; novel agents; resource-stratified
• ISSN: 1042-8194; 1029-2403
• DOI: 10.1080/10428194.2018.1427858

Predicated on our improved understanding of the disease biology, we have seen remarkable advances in the management of multiple myeloma over the past few years. Recently approved drugs have radically transformed the treatment paradigm and improved survivals of myeloma patients. The progress has necessitated revision of the diagnostic criteria, risk-stratification and response definition. The huge disparities in economy, healthcare infrastructure and access to novel drugs among different Asian countries will hinder the delivery of optimum myeloma care to patients managed in resource-constrained environments. In the light of the tremendous recent changes and evolution in myeloma management, it is timely that the resource-stratified guidelines from the Asian Myeloma Network be revised to provide updated recommendations for Asia physicians practicing under various healthcare reimbursement systems. This review will highlight the most recent advances and our recommendations on how they could be integrated in both resource-abundant and resource-constrained facilities.