Predictive value of thromboelastography for postoperative lower extremity deep venous thrombosis in gastric cancer complicated with portal hypertension patients

• Published in: Clinical and experimental hypertension (1993) Vol. 43; no. 2; pp. 196 - 202
• Main Authors: Gong, Chunhong, Yu, Kaihu, Zhang, Nianrong, Huang, Juan
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 17.02.2021; Taylor & Francis Group
• Subjects: Female; gastric cancer; Humans; Hypertension, Portal - etiology; Laparoscopy - adverse effects; Laparoscopy - methods; Laparotomy - adverse effects; Laparotomy - methods; lower extremity deep venous thrombosis; Male; Middle Aged; Outcome and Process Assessment, Health Care; portal hypertension; Postoperative Complications - diagnosis; Predictive Value of Tests; Prognosis; Stomach Neoplasms - complications; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; Thrombelastography - methods; Thromboelastography; Venous Thrombosis - diagnosis; Venous Thrombosis - etiology; Thromboelastography; portal hypertension; gastric cancer; prognosis; lower extremity deep venous thrombosis
• ISSN: 1064-1963; 1525-6006
• DOI: 10.1080/10641963.2020.1836194

To explore the predictive value of thromboelastography (TEG) for the occurrence of lower extremity deep venous thrombosis (LDVT) in gastric cancer combined with portal hypertension patients after operation. 172 gastric cancer patients combined with portal hypertension were randomly divided into laparoscopic surgery or laparotomy groups. All patients were taken venous blood on an empty stomach 1 day before operation, 1 day, 3 days, and 5 days after operation. There was no significant difference in R value, K value, α angle, and MA before and after operation (P > .05). Compared with the same group before operation, the R value and K value were decreased at 1, 3, and 5 days after operation, while the α angle and MA were increased (P < .05). Compared with the non-LDVT group, the postoperative R value and K value in the LDVT group were significantly lower, while the α angle and MA were significantly higher (P < .05). The AUC of R value, K value, α angle, and MA levels at 3 days after surgery to identify patients with LDVT was 0.778, 0.718, 0.881, and 0.781, respectively. The estimated probability of the final model for LDVT was 0.622. Compared with the estimated probability ≥0.622 group, the LDVT rate in the estimated probability <0.622 group was significantly increased (χ 2  = 60.128, P < .001). The combination of R value, K value, α angle, and MA at 3 days after surgery has a moderately effective predictive effect for the occurrence of LDVT in gastric cancer patients combined with portal hypertension.