Allergic granulomatosis and angiitis (Churg-Strauss)

An autopsy case of allergic granulomatosis and angiitis of Churg and Strauss is presented. The patient with a history of bronchial asthma of 3 years duration, a mild fever and hypereosinophilia, died in status asthmaticus. Cortocosteroid therapy was not given. The autopsy revealed severe eosinophili...

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Bibliographic Details
Published inActa pathologica japonica Vol. 30; no. 2; p. 335
Main Authors Oonishi, T, Ishiko, T
Format Journal Article
LanguageEnglish
Published Australia 01.03.1980
Subjects
Adult
Asthma - complications
Asthma - drug therapy
Bronchial Arteries - pathology
Cromolyn Sodium - therapeutic use
Eosinophilic Granuloma - complications
Eosinophilic Granuloma - pathology
Humans
Lung - pathology
Male
Portal Vein - pathology
Pulmonary Veins - pathology
Vasculitis - complications
Vasculitis - pathology
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Summary:An autopsy case of allergic granulomatosis and angiitis of Churg and Strauss is presented. The patient with a history of bronchial asthma of 3 years duration, a mild fever and hypereosinophilia, died in status asthmaticus. Cortocosteroid therapy was not given. The autopsy revealed severe eosinophilic pneumonia, disseminated necrotizing vasculitis of small arteries and veins in various stages, and extravascular granulomatous nodules. The involved organs were the lungs, liver and gastrointestinal tract, but the heart and kidneys were free from these lesions. The differences from the reported cases were discussed.
ISSN:0001-6632
DOI:10.1111/j.1440-1827.1980.tb01328.x