Immunology of COVID‐19

Summary The immune response to SARS‐CoV‐2 reveals a delicate balance between protective effects and harmful pathological reactions and can possibly explain the highly variable disease manifestations in subjects infected with this novel coronavirus. A better understanding of the anti‐viral immune res...

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Bibliographic Details
Published inEnvironmental microbiology Vol. 22; no. 12; pp. 4895 - 4908
Main Author Brüssow, Harald
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.12.2020
Wiley Subscription Services, Inc
Subjects
Animals
Coronaviruses
COVID-19
COVID-19 - immunology
COVID-19 - prevention & control
COVID-19 - virology
COVID-19 infection
COVID-19 Vaccines - immunology
Defence mechanisms
Disease control
Humans
Immune response
Immune system
Immunity
Immunology
microbiology
SARS-CoV-2 - immunology
Severe acute respiratory syndrome coronavirus 2
Vaccine development
Vaccines
Viral diseases
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Summary:Summary The immune response to SARS‐CoV‐2 reveals a delicate balance between protective effects and harmful pathological reactions and can possibly explain the highly variable disease manifestations in subjects infected with this novel coronavirus. A better understanding of the anti‐viral immune response is not only critical for vaccine development but might also provide targets for pharmaceutical and immunological treatment options. Recent research literature on immune aspects of COVID‐19 is summarized in this review with an outlook how bats have evolved to live with these viral infections.
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ISSN:1462-2912
1462-2920
1462-2920
DOI:10.1111/1462-2920.15302