Development of sensitive determination method for fungicides from environmental water samples with Titanate nanotube array micro-solid phase extraction prior to high performance liquid chromatography

• Published in: Chemosphere (Oxford) Vol. 90; no. 2; pp. 338 - 343
• Main Authors: Huang, Yunrui, Zhou, Qingxiang, Xie, Guohong
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.01.2013; Elsevier
• Subjects: Analysis methods; Analytical chemistry; Applied sciences; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography, High Pressure Liquid; detection limit; diethofencarb; Exact sciences and technology; Fungicides; Fungicides, Industrial - analysis; Fungicides, Industrial - chemistry; high performance liquid chromatography; metalaxyl; Micro-solid phase extraction; myclobutanil; nanotubes; Nanotubes - chemistry; Natural water pollution; Ordered TiO2 nanotube array; Other chromatographic methods; Pollution; solid phase extraction; Solid Phase Microextraction - methods; tebuconazole; thiram; Titanium - chemistry; titanium dioxide; Water Pollutants, Chemical - analysis; Water Pollutants, Chemical - chemistry; Water samples; Water treatment and pollution; Ordered TiO2 nanotube array; Micro-solid phase extraction; Fungicides; Water samples; Titanium IV Oxides; Solid phase extraction; Chemical analysis; Nanotube; HPLC chromatography; Ordered TiO; Waste water; Chemical enrichment; Freshwater environment; Sample preparation; Adsorbent; Quantitative analysis; nanotube array; Trace analysis; Pesticides; Fungicide; Solid phase microextraction; Reversed phase chromatography; Ultraviolet detector; Surface water; Lakes; Water pollution; River water; Nanostructured materials
• ISSN: 0045-6535; 1879-1298
• DOI: 10.1016/j.chemosphere.2012.07.024

► A micro-solid phase extraction was developed utilizing ordered TiO2 nanotube array. ► The developed method exhibited good enrichment performance for fungicides. ► Low LODs indicated that the developed method would be a valuable alternative. Fungicides have been widely used throughout the world, and the resulted pollution has absorbed great attention in recent years. Present study described an effective measurement technique for fungicides including thiram, metalaxyl, diethofencarb, myclobutanil and tebuconazole in environmental water samples. A micro-solid phase extraction (μSPE) was developed utilizing ordered TiO2 nanotube array for determination of target fungicides prior to a high performance liquid chromatography (HPLC). The experimental results indicated that TiO2 nanotube arrays demonstrated excellent merits on the preconcentration of fungicides, and excellent linear relationship between peak area and the concentration of fungicides was obtained in the range of 0.1–50μgL−1. The detection limits for the targeted fungicides were in the range of 0.016–0.086μgL−1 (S/N=3). Four real environmental water samples were used to validate the applicability of the proposed method, and good spiked recoveries in the range of 73.9–114% were achieved. A comparison of present method with conventional solid phase extraction was made and the results exhibited that proposed method resulted in better recoveries. The results demonstrated that this μ-SPE technique was a viable alternative for the analysis of fungicides in complex samples.