Stereospecific Synthesis of (−)-Neplanocin F

The stereospecific synthesis of (−)-neplanocin F was achieved in 15 steps from 2,3-O-isopropylidene-D-1,4-ribonolactone. The synthetic methodology can give an access through appropriate modifications to new series of carbanucleosides.

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Bibliographic Details
Published inNucleosides, nucleotides & nucleic acids Vol. 26; no. 8-9; pp. 1111 - 1114
Main Authors Ropero, Sergio Rodriguez, Edmont, Dolorès, Mathé, Christophe, Périgaud, Christian
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis Group 01.01.2007
Subjects
Adenosine - analogs & derivatives
Adenosine - chemical synthesis
Adenosine - chemistry
carbanucleoside
Methods
Molecular Structure
Neplanocin
Nucleosides - chemical synthesis
Nucleosides - chemistry
Stereoisomerism
stereospecific synthesis
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Summary:The stereospecific synthesis of (−)-neplanocin F was achieved in 15 steps from 2,3-O-isopropylidene-D-1,4-ribonolactone. The synthetic methodology can give an access through appropriate modifications to new series of carbanucleosides.
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ISSN:1525-7770
1532-2335
DOI:10.1080/15257770701521284